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Understanding Vivitrol Side Effects: What You Should Know

Vivitrol contains the active ingredient naltrexone, is a prescription drug, and is used in the prevention of alcohol relapse and opioid addiction. It is composed of naltrexone, which inhibits the effects of opioids and minimizes alcohol cravings. Although Vivitrol can be a valuable tool in the recovery process, it is essential to be aware of […]


Vivitrol contains the active ingredient naltrexone, is a prescription drug, and is used in the prevention of alcohol relapse and opioid addiction. It is composed of naltrexone, which inhibits the effects of opioids and minimizes alcohol cravings.

Although Vivitrol can be a valuable tool in the recovery process, it is essential to be aware of the potential side effects associated with this treatment and to have a background understanding of these factors.

What Is Vivitrol?

Vivitrol is a form of naltrexone in extended-release injection form, administered once a month and delivered intramuscularly. It is used under the framework of addiction treatment to treat users of opioids and alcohol.

How Vivitrol Works

  1. Blocks Opioid Effects: Vivitrol blocks opioid receptors in the brain, preventing the occurrence of a high.
  2. Reduces Alcohol Cravings: It has the effect of minimizing the craving to drink by influencing the reward system of the brain.
  3. Increased Sensitivity to Opioids: Once patients quit using Vivitrol, they become hypersensitive to opioids, which increases the possibility of experiencing opioid overdose if they relapse on opioids.

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Common Vivitrol Side Effects

Like most medications, Vivitrol may cause side effects. Being prepared can help you or your loved one make treatment more comfortable.

General Side Effects of Vivitrol

  1. Nausea
  2. Headache
  3. Dizziness
  4. Fatigue
  5. Loss of appetite
  6. Muscle cramps
  7. Joint pain
  8. Skin rash

Vivitrol Injection Site Reactions

The injection site of Vivitrol is one of the most reported cases. This includes:

  1. Redness
  2. Swelling
  3. Pain
  4. Hardening or lump at the injection site
  5. Open wound or intense pain (in rare cases)

Should there be any extreme skin issues, nervous conditions, or severe inflammation, dial 911 or call a medical practitioner as soon as you can.

Serious Side Effects of Vivitrol

While less common, some side effects can be severe. These include:

  1. Liver problems involving the discoloration of the skin or eyes, and dark urine
  2. Depression or suicidal thoughts
  3. Severe allergic reactions (rash, difficulty breathing)
  4. Pneumonia caused by injection (rare)
  5. Increased sensitivity to pain

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Naltrexone Shot Side Effects

Vivitrol, since it is a kind of injectable naltrexone, has the same side effects as naltrexone tablets, which include:

  1. Anxiety
  2. Insomnia
  3. Cold symptoms

You must always consult your doctor on these possible risks before using Vivitrol.

Who Should Not Use Vivitrol?

Vivitrol may not be suitable for everyone. It is not recommended for individuals who:

  1. Currently use opioids
  2. Have liver disease
  3. Are allergic to naltrexone
  4. Are pregnant or possibly might become pregnant, or are breastfeeding (check with a doctor)
  5. Have certain medical conditions that require hospitalization

Managing Vivitrol Side Effects

These are some of the tips for helpingwith the  mild side effects of Vivitrol.

  1. Stay Hydrated: Drinking water can be helpful with nausea and headaches.
  2. Monitor Injection Site: Apply a cold pack to the aching site.
  3. Communicate with Your Doctor: If you experience any new or worsening symptoms, be sure to mention them to your doctor.
  4. Emergency Treatment: Call 911 immediately when experiencing life-threatening allergic reactions, such as difficulty breathing and severe allergic reactions.

Vivitrol and Medical Supervision

Starting Vivitrol requires careful medical supervision. You should wait 7-14 days after being opioid-free to prevent precipitated withdrawal.

Why Medical Detox May Be Needed

  1. Helps clear opioids from your system safely
  2. Prepares your body for Vivitrol without complications

Vivitrol and Mental Health

A few individuals notice that they experience moodiness, depression, or anxiety when they utilize Vivitrol. It is important to keep track of mental health during treatment and consult medical professionals if or when needed.

Is Vivitrol Effective?

Evidence indicates that Vivitrol can help prevent relapse when it is used together with counseling and support. It is not a cure, but it is one component of a treatment plan.

Benefits of Vivitrol

  1. No daily pills required
  2. Non-addictive
  3. Reduces cravings and relapse risk
  4. Vivitrol prevents the impact of opioids, keeping people on the right track

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Vivitrol Intramuscular Injectable: What to Expect

When receiving a Vivitrol injection:

  1. It is administered in a healthcare setting.
  2. The shot is given in the buttocks muscle.
  3. It’s scheduled every 4 weeks.
  4. Vivitrol 380 mg, taken once monthly, is the standard dose.
  1. In which part of Spokane Valley, Washington, can a reputable facility to treat the side effects of Vivitrol be found?

    We Level Up Washington provides medical management and treatment for individuals affected by Vivitrol side effects. Our team ensures your treatment remains safe and effective.

  2. Where in Liberty Lake, WA can you find help with Vivitrol injection site issues?

    People of Liberty Lake can come to We Level Up Washington and find help when they need Vivitrol, medical detox, or addiction treatment.

  3. What is the location of Vivitrol addiction treatment in Spokane, WA?

    At We Level Up Washington, we offer full-fledged addiction recovery services to the people of Spokane, as well as managing the side effects of Vivitrol.

  4. How Long Do Vivitrol Side Effects Last?

    The mildest side effects of a dose of Vivitrol disappear after a few days of taking the injection of Vivitrol. Nonetheless, injection site reactions may take one or two weeks. Serious side effects require immediate medical attention.

Vivitrol and Substance Use Disorders

Vivitrol is primarily used to help treat:

  1. Alcohol use disorder
  2. Opioid use disorder

It works best as part of a complete addiction treatment plan that may include:

  1. Behavioral therapies
  2. Counseling
  3. Support groups

Vivitrol Safety Considerations

  1. Do not drink alcohol while using Vivitrol.
  2. Note that the opioid doses can become less effective or even hazardous when used in conjunction with Vivitrol.
  3. Adhere to medical monitoring and notify about the manifestation of symptoms of opioid withdrawal.
  4. Recognize that Vivitrol is an integral part of a comprehensive long-term recovery plan.

Final Thoughts

Vivitrol can be considered one of the most helpful means in the process of overcoming addiction, yet one should know about the potential side effects. You must be informed, and you can work with healthcare professionals who can help you navigate the treatment without any problems.

We Level Up Washington is ready to assist you or a loved one in case you consider pursuing Vivitrol treatment. Reach out to us now and learn more about Vivitrol, Vivitrol injections, and how we can support you on your road to recovery.

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